Month: October 2024

Nature Medicine, Published online: 30 October 2024; doi:10.1038/s41591-024-03215-z

Single-nucleus and single-cell RNA sequencing plus spatial profiling with four methods of core biopsies from 60 patients with metastatic breast cancer reveal patient-specific gene expression programs of breast cancer metastases that are maintained across time, site of metastasis and spatial profiling method, with spatial phenotypes correlating with microenvironmental features.

Nature Medicine, Published online: 30 October 2024; doi:10.1038/s41591-024-03308-9

Techniques for single-cell and spatial expression profiling hold great promise for defining the complexity of metastatic microenvironments, but different methods give different representations. We profile 67 biopsies of metastatic breast cancer using up to 6 different methods, provide a systematic comparison and reveal spatial aspects of breast cancer biology across diverse clinicopathological features.

The Dodgers have a chance to close out the Yankees in Game 4 of the World Series on Tuesday night. Follow along here for all the top moments and in-game analysis.

Garr's breakout role was as sexy Inga in Young Frankenstein. She earned an Oscar nomination for her role in the 1982 film Tootsie, and played Phoebe's mom on the sitcom Friends.

For the third and final installment of our Trilogy of Terror series, host Brittany Luse turns her attention to the ultimate taboo: cannibalism. Cannibalism stories have gotten big recently: it's in The Last of Us, Society of the Snow and Yellowjackets. She's joined by NPR Arts Desk reporter Neda Ulaby to dig deeper into three cannibalism films. They break down how versatile the trope is, what it says about how we consume – and how we love.

Everything you need to know about Paul vs. Tyson now that the fight is back on for November

It's giving iconic. It's giving legendary. It's giving award-winning femcees.

The post Missy Elliott, Queen Latifah Become First Rap Artists To Receive National Medal Of Arts appeared first on MadameNoire.

Thomas (ankle) will not appear in UNLV's season opener against Alabama State on Nov. 4, Mike Grimala of the Las Vegas Sun reports. Visit RotoWire.com for more analysis on this update.

Savile Row Travel has recently launched a new Safari Guide. Curated with luxury travellers in mind, it is an...

The post Embark on a bespoke African adventure with Savile Row’s new safari guide appeared first on A Luxury Travel Blog.

The action rolls on in the ring as fall brings us closer to the end of 2024