Nature Medicine, Published online: 17 April 2026; doi:10.1038/s41591-026-04405-7
Author Correction: Obicetrapib in patients with heterozygous familial hypercholesterolemia: the BROOKLYN randomized clinical trial- April 17, 2026
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Nature Medicine, Published online: 17 April 2026; doi:10.1038/s41591-026-04404-8
Publisher Correction: Reliability of LLMs as medical assistants for the general public: a randomized preregistered study- April 17, 2026
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Nature Medicine, Published online: 17 April 2026; doi:10.1038/s41591-026-04345-2
Should researchers avoid translational research in animals in favor of human or AI models? We argue that this debate should focus not on comparing species but instead on how experimental systems can be combined to maximize mechanistic confidence, human relevance, and real-world decision-making value.- April 17, 2026
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Nature Medicine, Published online: 17 April 2026; doi:10.1038/d41591-026-00021-7
Three phase 1/2 trials show that direct editing of HBG1 and HBG2 promoters is a promising disease‑agnostic strategy for treating β‑hemoglobinopathies such as sickle-cell disease and β-thalassemia.- April 17, 2026
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De La Calle introduced Strawberry Citrus, a fermented soda blending strawberry and citrus flavors with a low-sugar, functional profile. The launch underscores how brands are evolving traditional beverages with bold flavor, better-for-you positioning and cultural storytelling that resonates with modern consumers.
- April 16, 2026
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Nature Medicine, Published online: 16 April 2026; doi:10.1038/s41591-026-04331-8
Analyses of epidemiological, clinical and molecular data from a prospective cohort of 3,100 patients with esophageal carcinoma suggest intestinal metaplasia as a single precancer pathway preceding the disease.- April 16, 2026
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Nature Medicine, Published online: 16 April 2026; doi:10.1038/s41591-026-04340-7
In this phase 1/2 trial, patients with Ewing sarcoma received trabectedin and low-dose irinotecan at concentrations known to inhibit the activity of the transcription factor EWS::FLI1, leading to encouraging clinical response rates.- April 16, 2026
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Nature Medicine, Published online: 15 April 2026; doi:10.1038/s41591-026-04334-5
Drug-resistant fungal disease must be addressed in the 2026 update to the Global Action Plan on Antimicrobial Resistance- April 15, 2026
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Nature Medicine, Published online: 14 April 2026; doi:10.1038/d41591-026-00020-8
A phase 1 study evaluating setidegrasib shows promising safety and clinical activity, establishing targeted protein degradation as a viable new approach for treating KRAS G12D-driven solid tumors.- April 14, 2026
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Nature Medicine, Published online: 14 April 2026; doi:10.1038/s41591-026-04360-3
Antibiotic use over the past 8 years was associated with alterations in the gut microbiome composition in 14,979 individuals. These analyses integrated data from the Swedish National Prescribed Drug Register and stool metagenomic profiles. Alterations were found even after a single antibiotic course and varied markedly across different antibiotic classes.- April 14, 2026
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