Month: September 2025

Nature Medicine, Published online: 29 September 2025; doi:10.1038/s41591-025-03948-5

The US Food and Drug Administration (FDA) is at a crossroads. There is an urgent need to strengthen the integrity of drug approvals and rejections by diffusing the decision-making authority of individual officials and improving transparency when disagreements arise.
  • September 29, 2025
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Nature Medicine, Published online: 29 September 2025; doi:10.1038/s41591-025-03918-x

In the proof-of-concept phase 2 ROME trial, comprehensive genomic profiling followed by molecular tumor board evaluation and randomization of patients with metastatic solid cancer to receive personalized therapy or standard of care led to a significantly higher objective response rate and longer progression-free survival in patients who received personalized therapy.
  • September 29, 2025
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Nature Medicine, Published online: 29 September 2025; doi:10.1038/s41591-025-03977-0

A phase 3 trial found that VER-01, a full-spectrum cannabis extract, reduces chronic low back pain, improves physical function and sleep and shows no signs of dependence or withdrawal.
  • September 29, 2025
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Nature Medicine, Published online: 29 September 2025; doi:10.1038/s41591-025-03944-9

A post hoc analysis of a multicentre, randomised trial showed that prediabetes remission is possible without total weight loss—providing weight is distributed to subcutaneous deposits as opposed to visceral ones.
  • September 29, 2025
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The NFL Week 4 edition of Sunday Night Football saw the anticipated return of Micah Parsons to "Jerry World," as the Packers and Cowboys ended in the second-highest tie ever. Here are the highlights!
  • September 28, 2025
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US Reassesses Pre-Clearance Service in Canada Amid Travel Slump: What You Need To Know

US may end Pre-Clearance services at Canadian airports due to declining passenger numbers, potentially impacting Canadian airlines and US-Canada travel.

The post US Reassesses Pre-Clearance Service in Canada Amid Travel Slump: What You Need To Know appeared first on Travel And Tour World.
  • September 28, 2025
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Crawford had the interaction with police shortly after being honored by the city for his big win over Canelo Alvarez
  • September 28, 2025
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In 1999, Tony Hawk's "900" trick put a fresh spin on skateboarding. Now the board, helmet and other gear he used to land it have sold big at auction. Hawk tells us how it all came together.
  • September 28, 2025
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Meriam-Webster is revising one of its dictionaries to include many Gen Z words like "dad bod" and "cold brew."
  • September 28, 2025
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