Empagliflozin benefits in patients with heart failure and preserved ejection fraction

Empagliflozin benefits in patients with heart failure and preserved ejection fraction

Nature Medicine, Published online: 09 December 2022; doi:10.1038/s41591-022-02050-4

Subgroup analysis of the EMPEROR-Preserved clinical trial of the glucose-lowering drug empagliflozin in chronic heart failure with left ventricular ejection fraction (LVEF) >40% found improved clinical outcomes in the cohort of patients with LVEF ≥50%. This is, to our knowledge, the first time a drug therapy has been unequivocally demonstrated to benefit this patient population.

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Empagliflozin benefits in patients with heart failure and preserved ejection fraction

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