TRBC1-CAR T cell therapy in peripheral T cell lymphoma: a phase 1/2 trial
Nature Medicine, Published online: 11 November 2024; doi:10.1038/s41591-024-03326-7
In the dose-escalation part of the ongoing phase 1/2 LIBRA4 trial, patients with relapsed/refractory peripheral T cell lymphoma received T cell antigen receptor beta-chain constant domain 1 (TRBC1)-targeted chimeric antigen receptor T cell therapy, showing limited toxicity and encouraging preliminary clinical responses.
TRBC1-CAR T cell therapy in peripheral T cell lymphoma: a phase 1/2 trial
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