Genetic basis of early onset and progression of type 2 diabetes in South Asians

Genetic basis of early onset and progression of type 2 diabetes in South Asians

Nature Medicine, Published online: 26 November 2024; doi:10.1038/s41591-024-03317-8

In a cohort of 50,556 South Asian individuals, partitioned polygenic scores helped identify genetic susceptibility to insulin deficiency and unfavorable fat distribution as key drivers of young-onset T2D diagnosis and faster progression to diabetes-related complications.

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Genetic basis of early onset and progression of type 2 diabetes in South Asians

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