Integrating the environmental and genetic architectures of aging and mortality
Nature Medicine, Published online: 19 February 2025; doi:10.1038/s41591-024-03483-9
Based on a systematic analysis of environmental exposures associated with aging and mortality in the UK Biobank, the relative contributions of such exposures and genetic risk for mortality and a range of age-related diseases were compared, highlighting the potential beneficial effects of environment-focused interventions.
Integrating the environmental and genetic architectures of aging and mortality
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