A consensus blood transcriptomic framework for sepsis

A consensus blood transcriptomic framework for sepsis

Nature Medicine, Published online: 30 September 2025; doi:10.1038/s41591-025-03964-5

In a combined analysis of two large patient cohorts, three peripheral consensus transcriptomic subtypes of sepsis are identified, which can be linked to an 18-gene classifier associated with different odds of mortality and may offer a way to tailor care for patients with sepsis.

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A consensus blood transcriptomic framework for sepsis

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