A systematic review and meta-analysis of the efficacy and safety of pharmacological treatments for obesity in adults

A systematic review and meta-analysis of the efficacy and safety of pharmacological treatments for obesity in adults

Nature Medicine, Published online: 02 October 2025; doi:10.1038/s41591-025-03978-z

A systematic review and meta-analysis of clinical trials investigating the efficacy and safety of obesity management medications reported tirzepatide and semaglutide to be the most effective in reducing body weight and obesity-related complications.

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A systematic review and meta-analysis of the efficacy and safety of pharmacological treatments for obesity in adults

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