Developing cell therapies for lupus

Developing cell therapies for lupus

Nature Medicine, Published online: 10 October 2025; doi:10.1038/s41591-025-03987-y

Two phase 1 studies report promising outcomes with chimeric antigen receptor (CAR) T cell therapies in patients with systemic lupus erythematosus, but the next stage of development must address key pitfalls around comparator arms and ancillary immune-modulating treatments.

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Developing cell therapies for lupus

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