Budigalimab, an anti-PD-1 inhibitor, for people living with HIV-1: a randomized, placebo-controlled phase 1b study
Nature Medicine, Published online: 15 October 2025; doi:10.1038/s41591-025-03993-0
A randomized, controlled phase 1b trial evaluated the safety, pharmacokinetics and impact on viral kinetics of budigalimab, a PD-1 inhibitor, during analytical treatment interruption for HIV and found that it was well tolerated and resulted in delayed rebound in a subset of participants in an exploratory efficacy analysis.
Budigalimab, an anti-PD-1 inhibitor, for people living with HIV-1: a randomized, placebo-controlled phase 1b study
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