Base editing enables off-the-shelf CAR T cells for leukemia
Nature Medicine, Published online: 30 January 2026; doi:10.1038/d41591-026-00004-8
In patients with T cell acute lymphoblastic leukemia, base-edited CAR T cells — capable of destroying leukemic T cells while they themselves are protected — induced remission and allowed progression to stem-cell transplantation.
Base editing enables off-the-shelf CAR T cells for leukemia
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