Broad rim lesions are a new pathological and imaging biomarker for rapid disease progression in multiple sclerosis
Nature Medicine, Published online: 29 April 2025; doi:10.1038/s41591-025-03625-7
This study identifies a unique multiple sclerosis lesion, the broad rim lesion, which is associated with rapid disease progression and marked by a distinct inflammatory profile involving innate inflammation, cellular stress, unfolded protein response and apoptosis.
Broad rim lesions are a new pathological and imaging biomarker for rapid disease progression in multiple sclerosis
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