Nature Medicine, Published online: 21 February 2025; doi:10.1038/s41591-025-03511-2
A cluster randomized trial in China shows that telemedicine-based, village doctor-led delivery of integrated care reduced the occurrence of adverse cardiovascular events and hospitalizations in older adults with atrial fibrillation.- February 21, 2025
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Nature Medicine, Published online: 21 February 2025; doi:10.1038/s41591-025-03499-9
A longitudinal multiomics analysis of a patient with multiple myeloma who developed peripheral T cell lymphoma after treatment with anti-BCMA CAR T cells and a GPRC5D-directed bispecific antibody reveals that two mutated CAR+CD8+ T cell clones were probably drivers of the neoplasm.- February 21, 2025
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Nature Medicine, Published online: 21 February 2025; doi:10.1038/d41591-025-00014-y
The phase 3 CheckMate 8HW trial shows superior outcomes with nivolumab plus ipilimumab (compared with nivolumab monotherapy) in patients with microsatellite instability-high or mismatch repair-deficient metastatic colorectal cancer.- February 21, 2025
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Continue reading "Tulsi for weight loss: A natural way to reduce body fat"
- February 20, 2025
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Continue reading "Struggling with constipation? Here’s how prunes can help"
- February 19, 2025
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Nature Medicine, Published online: 19 February 2025; doi:10.1038/s41591-024-03483-9
Based on a systematic analysis of environmental exposures associated with aging and mortality in the UK Biobank, the relative contributions of such exposures and genetic risk for mortality and a range of age-related diseases were compared, highlighting the potential beneficial effects of environment-focused interventions.- February 19, 2025
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Nature Medicine, Published online: 19 February 2025; doi:10.1038/s41591-024-03356-1
In a clinical trial in pregnant women with gestational diabetes, a dietary intervention for energy restriction was safe and did not result in any difference in maternal weight or offspring standardized birth weight outcomes compared to the control arm.- February 19, 2025
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Nature Medicine, Published online: 19 February 2025; doi:10.1038/s41591-025-03536-7
We leveraged early-pregnancy prenatal cell-free DNA screening (PDNAS) sequencing data to determine tissue signatures associated with the development of preeclampsia. Next, we used these epigenetic signatures, as informed by nucleosome positioning, to build machine learning models to classify preeclampsia risk that we validated in distinct internal and external cohorts.- February 19, 2025
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Nature Medicine, Published online: 19 February 2025; doi:10.1038/s41591-025-03552-7
Interventions focused on disease prevention are a promising strategy for combating the rising incidence of dementia, but more evidence from clinical trials is needed to establish their feasibility and effectiveness.- February 19, 2025
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- February 18, 2025
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