Health

Nature Medicine, Published online: 24 July 2025; doi:10.1038/d41591-025-00046-4

A prospective implementation study shows how a low-cost, swallowable capsule sponge could be used for regular monitoring and risk stratification in people with Barrett’s esophagus, offering a minimally invasive alternative to endoscopy.

Nature Medicine, Published online: 24 July 2025; doi:10.1038/s41591-025-03845-x

Positive results from a first-in-human clinical trial validate the ANGPTL3–ANGPTL8 complex as a new therapeutic target for reducing triglycerides and, potentially, cardiovascular disease risk.

Nature Medicine, Published online: 24 July 2025; doi:10.1038/s41591-025-03804-6

Laurence Zitvogel reflects on the essential contribution of the immune system to the efficacy of anticancer chemotherapy.

Nature Medicine, Published online: 24 July 2025; doi:10.1038/s41591-025-03839-9

Connecting biomedical education with the medical humanities to advance translational medicine

Nature Medicine, Published online: 23 July 2025; doi:10.1038/s41591-025-03856-8

Using data from six population-scale cohorts involving more than 10 million individuals, a large language model-based aging signature is shown to outperform traditional aging biomarker indices and signatures in predicting multiple health outcomes, at general and organ-specific levels.

Nature Medicine, Published online: 23 July 2025; doi:10.1038/s41591-025-03838-w

Maximizing cascade genetic testing for disease prevention through direct notification of at-risk relatives

Nature Medicine, Published online: 22 July 2025; doi:10.1038/s41591-025-03817-1

In a phase 1b trial in three patients with Fanconi anemia, an irradiation- and busulfan-free conditioning regimen containing an anti-CD117 antibody, combined with T cell- and B cell-depleted haploidentical hematopoietic stem cell transplantation, was safe and led to high levels of donor engraftment.

In an effort to get real data on how much energy artificial intelligence uses, researchers at MIT Technology Review spoke to experts in the field. They determined that, depending on the large language model (LLM) used, a single AI text query can burn 6,706 joules per response, or about the same amount required to run a microwave oven for eight seconds. (In electricity, a joule is the amount of energy needed to emit one watt of power for one second.) That may not sound like much, but AI’s power consumption becomes more concerning when you imagine millions of people running dozens of text queries every day — and AI image and especially video generators use even more energy per query.

From iced lattes, soothing teas, and refreshing smoothies to ice creams, chocolates, and other culinary delights, matcha —the powdered green tea superfood —is having its moment! Its vibrant green colour, distinctive flavour, and list of health benefits continue to attract consumers, who are happily experimenting with this versatile ingredient. However, be cautious of consuming too …

Continue reading "Can matcha cause diarrhea? Know benefits and risk factors of this green superfood"

Nature Medicine, Published online: 21 July 2025; doi:10.1038/s41591-025-03799-0

A combination of animal studies, data from a clinical trial and insights from an observational cohort suggest that, in individuals with metabolic dysfunction-associated steatohepatitis, semaglutide improves liver histology by reverting patient proteomes to better mimic the proteome of individuals without the disease.