Health

Nature Medicine, Published online: 17 September 2025; doi:10.1038/s41591-025-03614-w

A purpose-built implantable system based on biomimetic epidural electrical stimulation of the spinal cord reduces the severity of hypotensive complications in people with spinal cord injury and improves quality of life.

Nature Medicine, Published online: 17 September 2025; doi:10.1038/s41591-025-03990-3

For exposome research to make a difference, it must be diversified and translate into policies that protect health.

Nature Medicine, Published online: 17 September 2025; doi:10.1038/s41591-025-03988-x

We created and curated three benchmark datasets to assess large language model (LLM) performance on sleep and fitness tasks ranging from answering expert questions to real-world coaching scenarios. Fine-tuning the Gemini LLM on real-world coaching tasks and self-reported sleep-quality outcomes improved its performance and provided a benchmark for further development.

Nature Medicine, Published online: 16 September 2025; doi:10.1038/s41591-025-03893-3

In an observational study comparing individuals with type 2 diabetes and obesity who underwent metabolic surgery with similar individuals who received GLP-1 receptor agonist treatment, metabolic surgery was associated with a lower risk of macrovascular and microvascular outcomes, including major adverse cardiovascular events, nephropathy, retinopathy and all-cause mortality.

Nature Medicine, Published online: 16 September 2025; doi:10.1038/s41591-025-03919-w

Interim trial results of MYR-101, a novel recombinant vector with selective tropism for oligodendrocytes, support its tolerability and indicate improved myelination and reduced cerebrospinal fluid N-acetyl-aspartic acid concentrations in children with Canavan disease.

Soaking beans may seem easy, but doing it right is important for making a creamy dish instead of a bland one. The soaking method you use can affect how long the beans take to cook and their final texture. There are two primary soaking methods, each with its benefits depending on your time and preferences. …

Continue reading "Want perfectly soaked beans? Don’t make this mistake that ruins your recipes"

A three-year study of child brain health and growth in the U.S., funded by the National Institutes of Health, has discovered that teens younger than 15 years old who experimented with cannabis, tobacco, or alcohol already exhibited brain differences before they ever started smoking or drinking. The findings suggest that preexisting factors that are detectable in brain mass may put certain kids at risk for substance abuse or addiction early in life. But, when detected, these signs can also help anticipate and address behaviors before they lead to drug and alcohol use.

Nature Medicine, Published online: 15 September 2025; doi:10.1038/s41591-025-03953-8

The STARD-AI statement, which was developed through a multistage process involving over 240 international stakeholders, provides a minimum set of criteria that allows for comprehensive reporting of AI-centered diagnostic test accuracy studies.

Nature Medicine, Published online: 15 September 2025; doi:10.1038/s41591-025-03965-4

A brief, self-administered digital cognitive test, in combination with a blood test, accurately detects clinical Alzheimer’s disease in primary care.