Health

According to the results of a long-term study published in the medical journal JAMA Network Open, people who begin using cannabis before the age of 15 are more likely to continue using the drug later in life. As the study participants aged into young adulthood, the nearly 20 percent who began using cannabis before turning 15 also showed a higher incidence of health problems like respiratory issues and accidental injuries then their peers who didn’t use the drug during adolescence, and were as much two to four times more likely to experience anxiety and depression.

Nature Medicine, Published online: 01 December 2025; doi:10.1038/s41591-025-04106-7

Results from the phase ELAD 2 trial reveal that liraglutide is safe and well tolerated in people with mild to moderate Alzheimer’s disease but does not significantly slow brain metabolism decline.

Nature Medicine, Published online: 01 December 2025; doi:10.1038/s41591-025-04092-w

San(g)s Frontières

Traditional remedies using herbs like turmeric, black cumin, and moringa have been cherished for their health benefits. Turmeric is well-known for its anti-inflammatory and antioxidant properties, aiding in blood sugar management and gut health. Black cumin contains thymoquinone, which offers antimicrobial and anti-inflammatory benefits, especially for respiratory issues. Moringa, once common in African and Asian …

Continue reading "Turmeric, black cumin, and moringa: Traditional uses and benefits of these healing herbs"

Nature Medicine, Published online: 28 November 2025; doi:10.1038/s41591-025-04054-2

In vivo experiments and clinical cohort analyses show that hypoxia-inducible factor 2 (HIF2)-induced parathyroid hormone-related protein (PTHrP) expression contributes to cachexia in the context of renal cell carcinoma (RCC). The pathway can be targeted by HIF2 inhibitors, including belzutifan, which may reduce cachexia in patients with RCC.

Nature Medicine, Published online: 27 November 2025; doi:10.1038/s41591-025-04061-3

Assessing the value of genomics is key to informing evidence-based policies; this Review outlines how current approaches to health technology assessment, implementation and data management can be adapted to suit the rapidly evolving technology and evidence base.

Nature Medicine, Published online: 27 November 2025; doi:10.1038/s41591-025-04118-3

Author Correction: Spatial multiomic landscape of the human placenta at molecular resolution

Nature Medicine, Published online: 26 November 2025; doi:10.1038/d41591-025-00068-y

A phase 1 trial suggests safety, tolerability and immunogenicity of a candidate subunit vaccine against the deadly Nipah virus, for which countermeasures are urgently needed.

Nature Medicine, Published online: 26 November 2025; doi:10.1038/s41591-025-04072-0

Author Correction: Neuroprotective role of Sirt1 in mammalian models of Huntington’s disease through activation of multiple Sirt1 targets

Nature Medicine, Published online: 25 November 2025; doi:10.1038/s41591-025-04050-6

The missing value of medical artificial intelligence