Health

Nature Medicine, Published online: 07 November 2025; doi:10.1038/s41591-025-04049-z

Elebsiran plus PEG-IFNα improved hepatitis B surface antigen (HBsAg) loss rates compared with PEG-IFNα alone in patients with chronic hepatitis B virus infection. Furthermore, prior response to the BRII-179 vaccine was associated with higher HBsAg clearance, suggesting its potential as a predictive tool for identifying patients more likely to benefit from therapies.

Nature Medicine, Published online: 06 November 2025; doi:10.1038/s41591-025-04057-z

In a meta-analysis of 48 randomized trials of chronic kidney disease progression, reduction in the 6-month urinary albumin:creatinine ratio was associated with lower hazard ratios of established kidney disease endpoints, supporting the use of albuminuria change as a surrogate endpoint in clinical trials for chronic kidney disease.

Methodology refinements grant hospitals more flexibility and provide more timely information to expectant parents

Nature Medicine, Published online: 05 November 2025; doi:10.1038/s41591-025-03982-3

Pretrained using 335,645 whole-slide images, a foundation model is developed to provide representations for slide- and patient-level tasks. It is capable of performing clinical tasks and generating reports even in data-scarce scenarios, such as rare cancer diagnosis and survival prediction, without requiring further fine-tuning.

Nature Medicine, Published online: 05 November 2025; doi:10.1038/s41591-025-04091-x

Publisher Correction: Academia Europaea’s guidelines for the visualization of clinical outcomes

Anxiety symptoms generally vary as per the age, gender, environmental factors, and personality type. If you are experience anxiety symptoms such as excessive worry, restlessness, irritability, irrational fear, overthinking or physical signs of anxiety including chest pain, IBS, nausea or more then it is advised to consult a professional therapist immediately. Holistic Living Wellness Studio, […]

The post Anxiety Symptoms and Treatment – Explained By Expert Psychologists first appeared on The Holistic Living.

Nature Medicine, Published online: 04 November 2025; doi:10.1038/s41591-025-04041-7

In this follow-up study presenting results at 96 weeks, cabotegravir and rilpivirine long-acting therapy remained noninferior to oral therapy, had acceptable safety and tolerability profiles, and resulted in durable virologic suppression, further supporting its consideration for African treatment programs.

November is National Alzheimer’s Disease Awareness Month. According to the Alzheimer’s Association, more than 7 million people in the United States suffer from Alzheimer’s, and almost 12 million Americans provide unpaid care for someone with the disease or another type of dementia. Watching someone you love experience changes in personality, behavior, and cognitive ability is painful and stressful. If it’s happening in your family, be sure to take care of yourselves and support each other, and remember that there are support groups available to help you through the process.

Nature Medicine, Published online: 03 November 2025; doi:10.1038/s41591-025-03955-6

In cognitively normal older adults at risk for Alzheimer’s dementia, physical inactivity was associated with faster tau protein buildup and cognitive decline.

Nature Medicine, Published online: 03 November 2025; doi:10.1038/s41591-025-04028-4

Shorena Janelidze recalls the discovery of phosphorylated tau, from early lab work to clinical implementation.