Health

Nature Medicine, Published online: 16 February 2026; doi:10.1038/s41591-026-04212-0

Using two newly developed immunoassays tested in three clinical cohorts, this study highlights CSF DOPA decarboxylase as a promising biomarker for differentiating dementia with Lewy bodies and Parkinson’s disease from Alzheimer’s disease and controls.

Nature Medicine, Published online: 16 February 2026; doi:10.1038/s41591-026-04258-0

Recent failures in high-profile clinical trials of neurodegenerative diseases highlight the need to rebalance clinical ambition and biological understanding.

Nature Medicine, Published online: 16 February 2026; doi:10.1038/s41591-026-04231-x

Precision nutrition must consider cost-effectiveness to deliver benefits to patients

Nature Medicine, Published online: 13 February 2026; doi:10.1038/s41591-026-04218-8

This Comment discusses how best to navigate an increasingly complex and dynamic research and innovation landscape in health.

Nature Medicine, Published online: 13 February 2026; doi:10.1038/s41591-026-04232-w

Inclusion by Design is a governance blueprint for auditable representation across trials and data infrastructures

Nature Medicine, Published online: 13 February 2026; doi:10.1038/d41591-026-00009-3

Climate change could result in an additional 123 million malaria cases in Africa by 2050, driven mostly by extreme weather events — which calls for climate-resilient malaria control strategies.

Many things in this world cannot be changed, but type 2 diabetes can be reversed. Research from the 2024–2025 American Diabetes Association (ADA) shows that dietary changes can improve how people manage diabetes. In some cases, these changes can even reverse the condition. You can regain your health and energy, and feel more in control, …

Continue reading "Type 2 diabetes reversal: 5 foods that could change your life"

Nature Medicine, Published online: 12 February 2026; doi:10.1038/s41591-026-04207-x

The authors developed a microfluidic device, FIND-Chip, designed to automate and enhance oocyte recovery from follicular fluid, a process traditionally done manually. When used in clinical settings, the device recovered additional oocytes missed during manual screening, substantially increasing the number of viable oocytes available for in vitro fertilization.

Nature Medicine, Published online: 12 February 2026; doi:10.1038/s41591-026-04208-w

A cluster-randomized trial in rural Lesotho showed that uncontrolled hypertension diagnosis and management delivered by minimally trained lay persons in the community using a mobile decision support tool was superior to facility referral for improving clinical outcomes.

Nature Medicine, Published online: 12 February 2026; doi:10.1038/s41591-025-04139-y

A follow-up analysis of a clinical trial that evaluated anti-PD-1 therapy in patients with cancer who are living with HIV provides mechanistic insights into transcriptomic, cellular and cytokine changes related to immune checkpoint inhibitor treatment and identifies a signature associated with clinical response.