Health

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Nature Medicine, Published online: 22 July 2025; doi:10.1038/s41591-025-03817-1

In a phase 1b trial in three patients with Fanconi anemia, an irradiation- and busulfan-free conditioning regimen containing an anti-CD117 antibody, combined with T cell- and B cell-depleted haploidentical hematopoietic stem cell transplantation, was safe and led to high levels of donor engraftment.
  • July 22, 2025
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In an effort to get real data on how much energy artificial intelligence uses, researchers at MIT Technology Review spoke to experts in the field. They determined that, depending on the large language model (LLM) used, a single AI text query can burn 6,706 joules per response, or about the same amount required to run a microwave oven for eight seconds. (In electricity, a joule is the amount of energy needed to emit one watt of power for one second.) That may not sound like much, but AI’s power consumption becomes more concerning when you imagine millions of people running dozens of text queries every day — and AI image and especially video generators use even more energy per query.
  • July 21, 2025
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From iced lattes, soothing teas, and refreshing smoothies to ice creams, chocolates, and other culinary delights, matcha —the powdered green tea superfood —is having its moment! Its vibrant green colour, distinctive flavour, and list of health benefits continue to attract consumers, who are happily experimenting with this versatile ingredient. However, be cautious of consuming too …
  • July 21, 2025
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Nature Medicine, Published online: 21 July 2025; doi:10.1038/s41591-025-03799-0

A combination of animal studies, data from a clinical trial and insights from an observational cohort suggest that, in individuals with metabolic dysfunction-associated steatohepatitis, semaglutide improves liver histology by reverting patient proteomes to better mimic the proteome of individuals without the disease.
  • July 21, 2025
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Nature Medicine, Published online: 21 July 2025; doi:10.1038/s41591-025-03895-1

Author Correction: Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
  • July 21, 2025
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Nature Medicine, Published online: 21 July 2025; doi:10.1038/s41591-025-03894-2

Author Correction: Sasanlimab plus BCG in BCG-naive, high-risk non-muscle invasive bladder cancer: the randomized phase 3 CREST trial
  • July 21, 2025
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Nature Medicine, Published online: 21 July 2025; doi:10.1038/s41591-025-03897-z

Publisher Correction: AI-enabled drug discovery reaches clinical milestone
  • July 21, 2025
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In the pursuit of effective weight loss solutions, individuals often seek natural and nutritious options that support their efforts. One such option that has gained popularity in recent years is chia seed water. Chia seeds have long been celebrated for their nutritional benefits, and when combined with water, they create a refreshing drink that can …
  • July 20, 2025
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Nature Medicine, Published online: 18 July 2025; doi:10.1038/s41591-025-03841-1

To facilitate the safe and effective implementation of autonomous artificial intelligence agents in healthcare, regulatory frameworks must evolve beyond static device paradigms to incorporate adaptive oversight and flexible pathways.
  • July 18, 2025
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Nature Medicine, Published online: 18 July 2025; doi:10.1038/s41591-025-03850-0

By systematic analysis of patient cases, we evaluated the clinical utility of open-source large language models (LLMs), such as the DeepSeek models, for implementation in medical applications. Their performance on clinical decision-making tasks was comparable to and partly better than proprietary models GPT-4o and Gemini-2.0 Flash Thinking Experimental, respectively.
  • July 18, 2025
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