Health

Nature Medicine, Published online: 10 January 2025; doi:10.1038/s41591-024-03406-8

Results from the phase 2 MATCH01 clinical trial of autologous monocyte-derived macrophage therapy for liver cirrhosis revealed no liver-related severe adverse events or deaths in the treatment group.

Nature Medicine, Published online: 10 January 2025; doi:10.1038/s41591-024-03447-z

Death of caregivers threaten child wellbeing. We estimate that 2.91 million children and adolescents in the USA had experienced death of a caregiver between 2000 and 2021. We describe the drivers of orphanhood and identify populations that are disproportionately affected. Our findings may inform policies and programs that address caregiver loss and its consequences.

Be it desserts, savory dishes, drinks, or skincare products, almonds appear in almost everything. In fact, the edible seeds of Prunus dulcis or the almond tree, are called the “King of Nuts.” They are celebrated not just for their versatility but also for their nutritional richness. Best known for boosting brain health, and helping in …

Continue reading "11 benefits of adding delicious almonds to your winter diet"

Ghee, a type of clarified butter, is a staple in many kitchens, especially in Indian cuisine. It is not just used to add a rich taste to your meals, but it is also packed with essential vitamins, healthy fats, and even gut-friendly properties. While ghee has been around for centuries and is praised for its …

Continue reading "Ghee benefits: 7 reasons this dairy delight is a must-have"

Nature Medicine, Published online: 09 January 2025; doi:10.1038/s41591-024-03431-7

An individual-based mathematical model evaluating the public health benefits of RSVpreF vaccination showed that vaccinating older adults and pregnant women can substantially reduce respiratory syncytial virus (RSV)-related hospitalizations and deaths, averting substantial inpatient costs, with the impact varying across countries and influenced by both uptake rates and the local epidemiological characteristics of RSV seasons.

Nature Medicine, Published online: 09 January 2025; doi:10.1038/s41591-024-03442-4

Premarital genomic screening in Arab populations of the Middle East

Nature Medicine, Published online: 08 January 2025; doi:10.1038/s41591-024-03429-1

In the second case in which a genetically modified pig heart was transplanted into a living person, the xenografted heart functioned well initially, but antibody-mediated rejection occurred thereafter, pointing to the need for improved strategies to avoid this complication.

Nature Medicine, Published online: 08 January 2025; doi:10.1038/s41591-024-03458-w

This analysis of the registry database DESCAR-T of more than 3,000 pediatric and adult patients with hematological malignancies who received CAR T cell therapy in France between 2018 and 2024 shows that only one person developed a secondary T cell malignancy following CAR T cell therapy.

Nature Medicine, Published online: 08 January 2025; doi:10.1038/d41591-025-00001-3

Satellite data assessing residential greenness across Italy indicate that thousands of deaths could be prevented by greening residential areas.

Nature Medicine, Published online: 08 January 2025; doi:10.1038/s41591-024-03455-z

KRAS mutations are ubiquitous in pancreatic adenocarcinomas (PDACs) and are associated with poor outcomes. We leveraged a cohort of 2,336 PDAC tumors to characterize genomic subtypes and their prognostic correlates across clinical stages. A key finding is that shallow copy gains in KRAS mutant alleles are common and indicate unfavorable prognosis.