Health

Nature Medicine, Published online: 27 October 2025; doi:10.1038/s41591-025-04066-y

Author Correction: A consensus immune dysregulation framework for sepsis and critical illnesses

Nature Medicine, Published online: 27 October 2025; doi:10.1038/s41591-025-04070-2

Author Correction: Cardiac gene therapy makes a comeback

Nature Medicine, Published online: 24 October 2025; doi:10.1038/s41591-025-04019-5

The future of HIV research — and of the USA’s scientific leadership — depends on bold, sustained action in defense of discovery, investment, and innovation.

Nature Medicine, Published online: 24 October 2025; doi:10.1038/d41591-025-00064-2

The first month-by-month analysis of malnutrition in children of preschool age in Gaza reveals the acute impact of aid restrictions and conflict — with the most recent estimates showing more than 50,000 children severely malnourished.

Nature Medicine, Published online: 21 October 2025; doi:10.1038/s41591-025-03969-0

In a phase 1 trial, intramuscular injection of synthetic plasmid DNA encoding monoclonal antibodies against SARS-CoV-2 was safe and well tolerated and did not elicit antidrug antibodies.

Nature Medicine, Published online: 21 October 2025; doi:10.1038/s41591-025-04011-z

In a phase 1 dose-escalation study including 11 patients with heart failure who were followed for 12 months, delivery of a cardiotropic adeno-associated viral vector designed to deliver constitutively active protein phosphatase 1 inhibitor 1 to the heart was well tolerated and showed preliminary evidence of efficacy.

Nature Medicine, Published online: 21 October 2025; doi:10.1038/s41591-025-04002-0

The first-in-human trial of AAV2i8-I1c (AB-1002) — an adenovirus vector that targets a protein phosphatase inhibitor to cardiac muscle — suggests a cautious return of cardiac gene therapy after earlier setbacks, with a new target, dose optimization and improved vector design shaping future directions.

Nature Medicine, Published online: 21 October 2025; doi:10.1038/s41591-025-04013-x

We must build safeguards against AI’s most dangerous feature: its ability to stop us thinking critically.

October was first declared National Bullying Prevention Month in 2006 by PACER’s National Bullying Prevention Center as a way for teens and adults to join together to stop bullying and cyberbullying. One in five students has been bullied at school in the past year, and research shows that 57 percent of kids who are bullied don’t notify an adult at school. But every teen can do something to help. Encourage respect for others, don’t give bullies an audience, and don’t ignore or shun those who are bullied. Wednesday, October 22, is “Unity Day,” when teens are encouraged to wear orange to show solidarity in uniting “for kindness, acceptance, and inclusion to prevent bullying.”

New approach parallels recent refinements to methodology behind Best Hospitals ratings