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We all know dry fruits are a great way to boost your health. Packed with nutrients, they are perfect for snacks, adding to meals, or just munching on throughout the day. From almonds to raisins, each one has its unique benefits. But did you know that cashews are one of the healthiest dry fruits you …

Continue reading "Cashew benefits: 7 surprising reasons why this dry fruit is good for you"

Nature Medicine, Published online: 07 January 2025; doi:10.1038/s41591-024-03451-3

In the final report of a phase 1 trial evaluating intracerebroventricular B7-H3-targeting CAR T cells in children and young adults with diffuse intrinsic pontine glioma, repeated intracranial infusions were feasible and well tolerated with a median overall survival of 19.8 months and 3 patients surviving over 40 months from diagnosis.

Nature Medicine, Published online: 07 January 2025; doi:10.1038/s41591-024-03375-y

A multicenter randomized controlled trial found that incorporating time-restricted eating, regardless of the timing of the eating window, into usual care—combining a Mediterranean diet with a nutritional education program—did not reduce visceral adipose tissue compared with usual care alone in adults with overweight or obesity.

Nature Medicine, Published online: 07 January 2025; doi:10.1038/s41591-024-03408-6

In a large-scale prospective study run across 12 sites in Germany and involving 463,094 women and 119 radiologists, AI-supported screening increased breast cancer detection rates by a significant margin without affecting the recall rate.

Nature Medicine, Published online: 07 January 2025; doi:10.1038/s41591-024-03421-9

In 1,088 pregnant individuals, assessment of abnormal serum angiogenic factors is demonstrated to be noninferior to the standard clinical approach based on estimated fetal weight and Doppler percentiles for the identification of fetuses at a higher risk of neonatal acidosis or Cesarean delivery, thus offering a beneficial option in settings where Doppler or experienced sonographers are not readily available.

The CDC is reporting a rise in norovirus outbreaks across the United States. Although it’s sometimes called the stomach flu, norovirus isn’t related to the flu. It is a highly contagious virus that causes gastroenteritis, an inflammation of the stomach and intestines.

Nature Medicine, Published online: 06 January 2025; doi:10.1038/s41591-024-03334-7

In this phase 1 trial, patients with locally advanced or metastatic solid tumors were treated with the individualized mRNA neoantigen-specific immunotherapy (iNeST) autogene cevumeran alone or in combination with the anti-PD-L1 agent atezolizumab, showing long-lasting neoantigen-specific immune responses and preliminary clinical activity, supporting further development of this therapeutic approach.

Nature Medicine, Published online: 06 January 2025; doi:10.1038/s41591-024-03398-5

Using multiple datasets from real-world evidence and completed trials, a machine learning model using routine blood and clinical data is shown to be predictive of patient response to immune checkpoint inhibitor therapy, across cancer types and outperforming standard biomarkers.

Nature Medicine, Published online: 06 January 2025; doi:10.1038/s41591-024-03364-1

CANAIRI: the Collaboration for Translational Artificial Intelligence Trials in healthcare