Nature Medicine, Published online: 28 April 2025; doi:10.1038/s41591-025-03700-z
Proteomics analyses of thousands of proteins in human cerebrospinal fluid reveal that the ratio of two proteins can be used to predict future dementia or cognitive resilience among people with Alzheimer’s disease brain pathology.- April 28, 2025
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Nature Medicine, Published online: 25 April 2025; doi:10.1038/s41591-025-03713-8
Author Correction: Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers- April 25, 2025
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Nature Medicine, Published online: 25 April 2025; doi:10.1038/s41591-025-03717-4
Author Correction: T cell malignancies after CAR T cell therapy in the DESCAR-T registry- April 25, 2025
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Nature Medicine, Published online: 23 April 2025; doi:10.1038/s41591-025-03639-1
A trial that used a master randomized design found that the skills commonly found in smartphone-based cognitive behavioral therapy, when tested alone or in combination with behavioral activation, were differentially efficacious in improving mental health symptoms in adults with subthreshold depression.- April 23, 2025
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Nature Medicine, Published online: 23 April 2025; doi:10.1038/s41591-025-03647-1
Analysis of multiple cohorts of patients with melanoma demonstrates a positive association between cytomegalovirus serostatus and overall survival in patients treated with monotherapy but not combination immune checkpoint blockade, as well as delayed onset of immune-related adverse events across both treatment types, as well as delayed development of metastatic disease in seropositive patients.- April 23, 2025
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Nature Medicine, Published online: 23 April 2025; doi:10.1038/s41591-025-03726-3
The open-source DeepSeek large language model showed variable performance relative to two leading models when benchmarked on four different medical tasks, with relatively strong reasoning capabilities but similar or weaker relative performance on other tasks, such as summarization of imaging reports.- April 23, 2025
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Nature Medicine, Published online: 23 April 2025; doi:10.1038/s41591-025-03727-2
In an evaluation involving 125 standardized patient cases, open-source DeepSeek large language models are shown to perform at least on par with state-of-the-art proprietary large language models in diagnosis and treatment recommendation tasks.- April 23, 2025
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This latest innovation provides bakers with a powerful, effective alternative to artificial preservatives, making it easier than ever to meet market demands for cleaner ingredient lists and extended freshness.
- April 22, 2025
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Nature Medicine, Published online: 22 April 2025; doi:10.1038/s41591-025-03624-8
Systematic analysis from the Global Burden of Disease study reported that, despite global improvements from 1990 to 2021, dietary iron deficiency-associated disease burden remains high in women, children and residents in low socio-demographic index countries.- April 22, 2025
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Nature Medicine, Published online: 22 April 2025; doi:10.1038/s41591-025-03656-0
Administration of an antisense oligonuceotide in a preterm infant with severe early-onset SCN2A developmental and epileptic encephalopathy was well tolerated and led to a 60% decrease in seizure frequency.- April 22, 2025
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