Health

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Nature Medicine, Published online: 10 February 2025; doi:10.1038/s41591-025-03516-x

In a large-scale analysis of ambulatory electrocardiographic recordings, a deep learning algorithm had a substantially higher sensitivity for the detection of critical arrhythmias as compared to technicians, opening a path toward artificial intelligence-assisted direct-to-physician reporting of ambulatory electrocardiography results.
  • February 10, 2025
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Nature Medicine, Published online: 10 February 2025; doi:10.1038/s41591-025-03494-0

A rare case of asymptomatic dominantly inherited Alzheimer’s reveals confined tau pathology and unique proteomic features, highlighting potential resilience mechanisms decades beyond expected onset.
  • February 10, 2025
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Nature Medicine, Published online: 10 February 2025; doi:10.1038/s41591-025-03508-x

Epigenetic editing of PCSK9 in the liver, designed to induce DNA methylation and silence gene expression, achieved long-lasting reductions in LDL cholesterol levels in both transgenic mice expressing the human PCSK9 gene and cynomolgus monkeys.
  • February 10, 2025
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Nature Medicine, Published online: 10 February 2025; doi:10.1038/s41591-024-03400-0

Two new phosphorylation sites, p-tau262 and p-tau356, detect the formation of prefibrillar tau aggregates and may serve as early-stage biofluid-based biomarkers of tau neurofibrillary tangle pathology in Alzheimer’s disease.
  • February 10, 2025
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There are many medicinal plants that can be beneficial for your health. Tulsi or holy basil, and ashwagandha probably top that list. While those are essential, you must also include stinging nettle or Urtica dioica. This plant is small in size with hair-like structures that cause stinging sensations upon contact with skin. But don’t let …
  • February 9, 2025
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If you are looking for a plant-based protein and calcium source, Greek yoghurt is a must-have. This creamy, tangy, and undeniably delicious yoghurt is more than just a tasty treat. It is also a nutritional powerhouse, packed with benefits that extend far beyond its protein-rich profile. Not only does its high protein content help you …
  • February 8, 2025
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Matcha, a green-coloured powder, is widely enjoyed as hot tea. The powder made from green tea leaves can also be added to smoothies, cookies, and boba tea. It is not only loved because of its vibrant colour or its earthy, umami flavour, it consists of antioxidants, including polyphenols, that can be great for your health. …
  • February 7, 2025
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Nature Medicine, Published online: 07 February 2025; doi:10.1038/s41591-025-03537-6

Multiple maternal conditions in pregnancy have been associated with autism risk in the child. However, analysis of family data from over a million children indicates that causality is unlikely; instead, these associations probably arise from genetic and other familial factors.
  • February 7, 2025
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Nature Medicine, Published online: 07 February 2025; doi:10.1038/s41591-025-03510-3

A small but in-depth study of allogeneic CAR T cell therapy in patients with high-risk neuroblastoma shows feasibility and potential efficacy, and mechanistic insights reveal pathways to improved functionality of CAR T cells in solid tumors.
  • February 7, 2025
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Nature Medicine, Published online: 07 February 2025; doi:10.1038/s41591-024-03467-9

New evidence suggests that Ruminococcus gnavus in the gut induces monoamine synthesis and neurotoxicity in some patients with cirrhosis, causing hepatic encephalopathy — revealing a possible therapeutic target or predictive biomarker for this understudied condition.
  • February 7, 2025
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