Nature Medicine, Published online: 10 February 2025; doi:10.1038/s41591-025-03516-x
In a large-scale analysis of ambulatory electrocardiographic recordings, a deep learning algorithm had a substantially higher sensitivity for the detection of critical arrhythmias as compared to technicians, opening a path toward artificial intelligence-assisted direct-to-physician reporting of ambulatory electrocardiography results.- February 10, 2025
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Nature Medicine, Published online: 10 February 2025; doi:10.1038/s41591-025-03494-0
A rare case of asymptomatic dominantly inherited Alzheimer’s reveals confined tau pathology and unique proteomic features, highlighting potential resilience mechanisms decades beyond expected onset.- February 10, 2025
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Nature Medicine, Published online: 10 February 2025; doi:10.1038/s41591-025-03508-x
Epigenetic editing of PCSK9 in the liver, designed to induce DNA methylation and silence gene expression, achieved long-lasting reductions in LDL cholesterol levels in both transgenic mice expressing the human PCSK9 gene and cynomolgus monkeys.- February 10, 2025
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Nature Medicine, Published online: 10 February 2025; doi:10.1038/s41591-024-03400-0
Two new phosphorylation sites, p-tau262 and p-tau356, detect the formation of prefibrillar tau aggregates and may serve as early-stage biofluid-based biomarkers of tau neurofibrillary tangle pathology in Alzheimer’s disease.- February 10, 2025
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- February 9, 2025
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Continue reading "Greek yoghurt: 5 reasons why you should have it every day"
- February 8, 2025
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Continue reading "Drinking matcha tea every day? 9 ways it can improve your health"
- February 7, 2025
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Nature Medicine, Published online: 07 February 2025; doi:10.1038/s41591-025-03537-6
Multiple maternal conditions in pregnancy have been associated with autism risk in the child. However, analysis of family data from over a million children indicates that causality is unlikely; instead, these associations probably arise from genetic and other familial factors.- February 7, 2025
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Nature Medicine, Published online: 07 February 2025; doi:10.1038/s41591-025-03510-3
A small but in-depth study of allogeneic CAR T cell therapy in patients with high-risk neuroblastoma shows feasibility and potential efficacy, and mechanistic insights reveal pathways to improved functionality of CAR T cells in solid tumors.- February 7, 2025
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Nature Medicine, Published online: 07 February 2025; doi:10.1038/s41591-024-03467-9
New evidence suggests that Ruminococcus gnavus in the gut induces monoamine synthesis and neurotoxicity in some patients with cirrhosis, causing hepatic encephalopathy — revealing a possible therapeutic target or predictive biomarker for this understudied condition.- February 7, 2025
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