Health

Be careful which performance-enhancing dietary supplements you spend your money on. For example, creatine—popular with teen athletes for building muscle—hasn’t been studied for adolescent use. According to Rebecca Carl, chair of the American Academy of Pediatrics’ Council on Sports Medicine and Fitness, “More recent reviews suggest that creatine can be used safely, but these are generally studies of adults.” Your body produces creatine naturally, and gets it from foods you eat like salmon, eggs, and dairy products. And while creatine supplements may be useful for quick bursts of strength and energy, they aren’t likely to aid in overall performance. “There’s not a benefit for certainly any sport where there’s an endurance component of it,” says Carl.

Nature Medicine, Published online: 07 July 2025; doi:10.1038/s41591-025-03793-6

Global estimates of expected and preventable gastric cancers in people born between 2008 and 2017 report that there will be 15.6 million lifetime gastric cancer cases, three-quarters of which are preventable through H. pylori eradication measures.

Nature Medicine, Published online: 07 July 2025; doi:10.1038/s41591-025-03826-0

Thirty years of Europe’s centralized procedure for approving medicines

Nature Medicine, Published online: 04 July 2025; doi:10.1038/s41591-025-03789-2

When tested in a multiethnic cohort of ~2.5 million US veterans, the PREVENT equations, recently developed by the American Heart Association for sex-specific and race-free prediction of cardiovascular disease risk, were shown to accurately estimate this risk with some variability across race and ethnicity groups and to outperform the previously used pooled cohort equation risk score.

Nature Medicine, Published online: 03 July 2025; doi:10.1038/d41591-025-00043-7

Instead of making one-off treatments, industrialized gene therapy might be able to treat multiple diseases.

Nature Medicine, Published online: 03 July 2025; doi:10.1038/s41591-025-03815-3

Trials for LLM-supported clinical decisions in African primary healthcare

Nature Medicine, Published online: 03 July 2025; doi:10.1038/s41591-025-03806-4

Co-designing a public health data analytics platform

Nature Medicine, Published online: 02 July 2025; doi:10.1038/s41591-025-03773-w

Preliminary results from an investigator-initiated clinical trial showed that an AAV-OTOF gene therapy was safe and led to hearing improvements in ten patients with congenital deafness with 6–12 months of follow-up, including in a teenager and a young adult, expanding the age range from previous trials.

Nature Medicine, Published online: 02 July 2025; doi:10.1038/s41591-025-03796-3

Campaigners want ultra-processed foods to be better defined and regulated. But does the evidence support strong policy changes?

Nature Medicine, Published online: 02 July 2025; doi:10.1038/s41591-025-03755-y

An explosion of digital tools and AI is catalyzing innovations in the mission to scale up mental health support worldwide. These paradigms currently rely on a ‘human in the loop’ — but who is the human in question, and does it matter?