Circulating metabolites, genetics and lifestyle factors in relation to future risk of type 2 diabetes
Nature Medicine, Published online: 14 January 2026; doi:10.1038/s41591-025-04105-8
Researchers studied the blood-based metabolome of over 23,000 people from ten ethnically diverse cohorts. They identified 235 metabolites associated with future risk of type 2 diabetes (T2D). By integrating genetic and modifiable lifestyle factors, their findings provide insights into T2D mechanisms and could improve risk prediction and inform precision prevention.
Circulating metabolites, genetics and lifestyle factors in relation to future risk of type 2 diabetes
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