Concurrent intrathecal and intravenous nivolumab in leptomeningeal disease: phase 1 trial interim results
Nature Medicine, Published online: 30 March 2023; doi:10.1038/s41591-022-02170-x
In an interim analysis of a phase 1 trial of concurrent intrathecal and intravenous anti-PD1 delivery in patients with leptomeningeal disease and melanoma, treatment was feasible and well-tolerated with no dose-limiting toxicities.
Concurrent intrathecal and intravenous nivolumab in leptomeningeal disease: phase 1 trial interim results
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