Effect of felzartamab on the molecular phenotype of antibody-mediated rejection in kidney transplant biopsies

Effect of felzartamab on the molecular phenotype of antibody-mediated rejection in kidney transplant biopsies

Nature Medicine, Published online: 29 April 2025; doi:10.1038/s41591-025-03653-3

Molecular analyses of longitudinal kidney biopsies from a phase 2 trial testing an anti-CD38 antibody for kidney transplant rejection show temporary suppression of antibody-mediated rejection during treatment, with molecular recurrence at 52 weeks.

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Effect of felzartamab on the molecular phenotype of antibody-mediated rejection in kidney transplant biopsies

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