Effects of vutrisiran on cardiac structure and function in patients with transthyretin amyloidosis with cardiomyopathy: secondary outcomes of the HELIOS-B trial
Nature Medicine, Published online: 06 August 2025; doi:10.1038/s41591-025-03851-z
In the HELIOS-B randomized trial in patients with transthyretin amyloid cardiomyopathy, treatment with the RNA interference agent vutrisiran, which targets transthyretin, led to improved echocardiographic measures of cardiac structure and function, as compared to placebo.
Effects of vutrisiran on cardiac structure and function in patients with transthyretin amyloidosis with cardiomyopathy: secondary outcomes of the HELIOS-B trial
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