Extracorporeal cross-circulation with genetically modified pig livers in a human decedent model
Nature Medicine, Published online: 11 February 2026; doi:10.1038/s41591-026-04224-w
Extracorporeal liver cross-circulation using genetically modified pig livers was feasible in a human decedent model, providing effective temporary liver support with minimal immunosuppression. In this model, xenograft integrity was preserved, and metabolic and hemodynamic stability were maintained even after removal of the native human liver in the decedent.
Extracorporeal cross-circulation with genetically modified pig livers in a human decedent model
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