Interplay of genetic predisposition, plasma metabolome and Mediterranean diet in dementia risk and cognitive function

Interplay of genetic predisposition, plasma metabolome and Mediterranean diet in dementia risk and cognitive function

Nature Medicine, Published online: 25 August 2025; doi:10.1038/s41591-025-03891-5

Genetic background, plasma metabolome and dietary data from 4,215 women and 1,490 men reveal 57 metabolites whose associations with dementia risk vary by APOE4 genotype and other risk variants.

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Interplay of genetic predisposition, plasma metabolome and Mediterranean diet in dementia risk and cognitive function

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