Neoadjuvant triplet immune checkpoint blockade in newly diagnosed glioblastoma
Nature Medicine, Published online: 27 February 2025; doi:10.1038/s41591-025-03512-1
A patient with newly diagnosed glioblastoma was safely treated with neoadjuvant nivolumab, relatlimab and ipilimumab before maximal resection, with comprehensive immune profiling showing the induction of overall immune activation early during treatment. The patient had no definitive evidence of recurrence at 17 months after treatment.
Neoadjuvant triplet immune checkpoint blockade in newly diagnosed glioblastoma
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