Neoantigen immunogenicity landscapes and evolution of tumor ecosystems during immunotherapy with nivolumab
Nature Medicine, Published online: 30 September 2024; doi:10.1038/s41591-024-03240-y
In this biomarker cohort analysis of CheckMate 153, analyses of genomic alterations and neoepitope immunogenicity in tumor tissue samples from patients with non-small cell lung cancer treated with nivolumab show the evolution of neoantigens during nivolumab-induced selection pressure and how it associates with clinical response.
Neoantigen immunogenicity landscapes and evolution of tumor ecosystems during immunotherapy with nivolumab
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