Partitioned polygenic risk scores identify distinct types of metabolic dysfunction-associated steatotic liver disease

Partitioned polygenic risk scores identify distinct types of metabolic dysfunction-associated steatotic liver disease

Nature Medicine, Published online: 09 December 2024; doi:10.1038/s41591-024-03284-0

The application of partitioned polygenic scores to data from cohorts of patients identifies two distinct subtypes of MASLD with different cardiometabolic risk profiles.

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Partitioned polygenic risk scores identify distinct types of metabolic dysfunction-associated steatotic liver disease

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