Postoperative circulating tumor DNA could guide CRC adjuvant treatment

Postoperative circulating tumor DNA could guide CRC adjuvant treatment

Nature Medicine, Published online: 16 January 2023; doi:10.1038/s41591-022-02119-0

The large, ongoing CIRCULATE-Japan trial is investigating the role of circulating tumor DNA (ctDNA)-based molecular residual disease testing in patients with resectable colorectal cancer after radical surgery. An interim analysis of GALAXY, a prospective, observational arm of CIRCULATE-Japan, establishes ctDNA as a prognostic and predictive biomarker.

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Postoperative circulating tumor DNA could guide CRC adjuvant treatment

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