Seeking therapeutic synergy in BRAF mutant colorectal cancer
Nature Medicine, Published online: 31 January 2023; doi:10.1038/s41591-022-02192-5
In a phase I trial, the combination of dabrafenib, trametinib and spartalizumab uncovers the crosstalk between the MAPK pathway and the immune system, which offers a promising new strategy to improve clinical outcomes.
Seeking therapeutic synergy in BRAF mutant colorectal cancer
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