Surgery versus no surgery in platinum-sensitive relapsed ovarian cancer: final overall survival analysis of the SOC-1 randomized phase 3 trial
Nature Medicine, Published online: 01 June 2024; doi:10.1038/s41591-024-02981-0
In a phase 3 randomized controlled trial comparing secondary cytoreduction plus chemotherapy versus chemotherapy alone in patients with relapsed ovarian cancer, the coprimary endpoint of overall survival was not statistically different, but in a prespecified sensitivity analysis adjusted for patients who underwent crossover surgery following tumor relapse, there was an increase in overall survival.
Surgery versus no surgery in platinum-sensitive relapsed ovarian cancer: final overall survival analysis of the SOC-1 randomized phase 3 trial
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