health

Nature Medicine, Published online: 06 November 2024; doi:10.1038/s41591-024-03365-0

We report the first case of a person achieving sustained HIV-1 remission after transplantation with allogeneic hematopoietic stem cells that express wild-type CCR5 and thus are permissive to HIV-1 infection. The 53-year-old man received the transplant in 2018 to treat a rare myeloid sarcoma and has not experienced viral rebound since discontinuing antiretroviral therapy in November 2021.

Nature Medicine, Published online: 05 November 2024; doi:10.1038/s41591-024-03395-8

A systematic review and meta-analysis of studies covering 66 countries reported wide-ranging maternal, fetal and neonatal health harms associated with heat exposure, including increased risks of preterm birth, stillbirths, obstetric complications, congenital anomalies and gestational diabetes.

Olive oil, a natural oil extracted from the fruit of the olive tree, is a common kitchen ingredient. This oil is created by pressing or crushing olives and has high antioxidants and anti-inflammatory compounds, particularly polyphenols. It is available in different types, including extra virgin ones, and may be beneficial for your heart and skin …

Continue reading "Olive oil for weight loss: Does it work?"

Nature Medicine, Published online: 04 November 2024; doi:10.1038/s41591-024-03301-2

In a prospective, regulatory-grade study of assistance to pathologists in MASH histology scoring, AIM-MASH-assisted reads by expert MASH pathologists were superior to unassisted reads and decreased inter-reader variability.

Shifting the clocks by an hour for daylight savings time may seem small, but it can mess with your internal body clock, making it harder to fall asleep or feel rested in the morning. If you’re already battling late nights and early wake-ups because of school and activities, this extra disruption can leave you feeling groggy, stressed, or less focused.

Who would have guessed that a sweet, chewy delicacy, like a date, could be used to shed extra kilos. Eating dates for weight loss can prove to be effective as these are packed with natural sugars and fibre, What’s more? These delicious fruits are filled with nutrients and are low in calories, making them the …

Continue reading "Dates for weight loss: 8 ways it can help you get back in shape"

Nature Medicine, Published online: 31 October 2024; doi:10.1038/d41591-024-00077-3

In British South Asian women, a culturally adapted and community-informed cognitive behavioral therapy intervention led to higher early recovery rates than the usual treatment.

Nature Medicine, Published online: 31 October 2024; doi:10.1038/d41591-024-00076-4

The twentieth century saw unprecedented rises in life expectancy in high-income countries, but data suggest that this trend will not continue in the current century without radical interventions to slow biological aging.

Nature Medicine, Published online: 30 October 2024; doi:10.1038/s41591-024-03215-z

Single-nucleus and single-cell RNA sequencing plus spatial profiling with four methods of core biopsies from 60 patients with metastatic breast cancer reveal patient-specific gene expression programs of breast cancer metastases that are maintained across time, site of metastasis and spatial profiling method, with spatial phenotypes correlating with microenvironmental features.

Nature Medicine, Published online: 30 October 2024; doi:10.1038/s41591-024-03308-9

Techniques for single-cell and spatial expression profiling hold great promise for defining the complexity of metastatic microenvironments, but different methods give different representations. We profile 67 biopsies of metastatic breast cancer using up to 6 different methods, provide a systematic comparison and reveal spatial aspects of breast cancer biology across diverse clinicopathological features.