health

Nature Medicine, Published online: 31 March 2025; doi:10.1038/s41591-025-03593-y

The role of distress in female sexual dysfunction during menopause

Nature Medicine, Published online: 31 March 2025; doi:10.1038/s41591-025-03607-9

A detailed case report shows that neoadjuvant combination immunotherapy can activate antitumor immunity and drive clinical benefit in newly diagnosed glioblastoma, revealing avenues for further research that could shift the treatment landscape to improve survival.

Nature Medicine, Published online: 31 March 2025; doi:10.1038/s41591-025-03675-x

Author Correction: Bioaccumulation of microplastics in decedent human brains

Nature Medicine, Published online: 30 March 2025; doi:10.1038/s41591-025-03628-4

While fluid restriction is typically recommended for patients with chronic heart failure, this randomized clinical trial showed no difference in health status, as assessed by patient-reported outcomes, between patients recommended to a liberal versus a restrictive fluid regimen over the course of 3 months in an outpatient setting.

Nature Medicine, Published online: 30 March 2025; doi:10.1038/s41591-025-03671-1

This systematic review and meta-analysis provides an updated assessment of the efficacy and safety of intravenous iron therapy in patients with heart failure and iron deficiency, incorporating the results of the newly conducted FAIF-HF2 trial.

Nature Medicine, Published online: 28 March 2025; doi:10.1038/s41591-025-03665-z

Author Correction: A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features

Nature Medicine, Published online: 28 March 2025; doi:10.1038/d41591-025-00022-y

Foreign aid sanctions reverse progress on child and maternal health and increase mortality rates, according to an analysis of three decades’ worth of data from 113 countries.

Nature Medicine, Published online: 28 March 2025; doi:10.1038/s41591-025-03664-0

Author Correction: Microglial mechanisms drive amyloid-β clearance in immunized patients with Alzheimer’s disease

Nature Medicine, Published online: 28 March 2025; doi:10.1038/s41591-025-03557-2

Two recent, early-phase trials evaluating antibodies that target GDF-15 show positive effects on immunotherapy response and cachexia symptoms; further work to unravel the multifaceted biology of GDF-15 in cancer could lead to transformative treatment strategies.

Nature Medicine, Published online: 27 March 2025; doi:10.1038/s41591-025-03594-x

Conflict zones are plagued by air pollution from warfare-related activities, which exacerbates public health challenges, especially for vulnerable populations and the environments they live in.