health

Nature Medicine, Published online: 07 October 2025; doi:10.1038/s41591-025-03961-8

In the randomized phase 3 AMPLITUDE trial, patients with HRR-deficient mCSPC experienced longer progression-free survival when they were treated with niraparib and AAP compared to placebo and AAP.

Nature Medicine, Published online: 07 October 2025; doi:10.1038/s41591-025-03998-9

In this multicentered observational study, Rotavac, an indigenous, monovalent, live, attenuated, oral rotavirus vaccine, had an adjusted vaccine efficacy of 54% and protected against severe gastroenteritis in Indian children during its rollout between 2016 and 2020.

A series of studies conducted by researchers at Cornell University and MIT in 2023, and published this May in the journal Personality and Social Psychology Bulletin, found that people who believe conspiracy theories are unusually overconfident in their beliefs, and greatly overestimate how many people agree with them. For instance, in one study sample only 8 percent of the nearly 5,000 participants thought that a wild claim popularized on social media was true, but that the 8 percent who thought it was true also believed that 61 percent of other people thought it was true. “What we observed is that [some people] tend to strongly believe these conspiracies despite the fact that there’s counter evidence or a lot of people disagree,” psychologist and study co-author Gordon Pennycook notes. “Having overconfidence is that buffer that stops you from learning from other people. You end up not just going down the rabbit hole, you’re doing laps down there.”

Nature Medicine, Published online: 06 October 2025; doi:10.1038/s41591-025-03971-6

In the double-blind, placebo-controlled phase 2 ARGO trial, patients with active psoriatic arthritis treated with a nanobody targeting IL-17A and IL-17F showed substantially better disease response rates compared with those receiving placebo treatment.

Nature Medicine, Published online: 06 October 2025; doi:10.1038/s41591-025-03983-2

This Review summarizes recent technical advancements in generative AI, outlines how new models might improve healthcare and discusses validation approaches—using lessons from recent successes and failures in the field.

Nature Medicine, Published online: 06 October 2025; doi:10.1038/s41591-025-04037-3

In a cross-trial analysis, combined treatment with medications that have individually shown to improve cardiovascular outcomes in heart failure with mildly reduced or preserved ejection fraction demonstrates substantial benefit, including for event-free survival.

Nature Medicine, Published online: 06 October 2025; doi:10.1038/s41591-025-03974-3

A modeling approach to assess the global risk of Plasmodium falciparum histidine-rich protein 2 and 3 gene deletions identifies ten priority African countries for surveillance and could inform malaria control policies.

When it comes to gut health, almonds can be the perfect nuts as they’re packed with nutrition that can really boost your digestion. They’re high in protein and loaded with prebiotics, which feed the good bacteria in your gut. By adding these crunchy little gems to your meals or munching on them throughout the day, …

Continue reading "Do almonds have prebiotics? Dietitian explains why they are good for your gut health"

Nature Medicine, Published online: 02 October 2025; doi:10.1038/s41591-025-03978-z

A systematic review and meta-analysis of clinical trials investigating the efficacy and safety of obesity management medications reported tirzepatide and semaglutide to be the most effective in reducing body weight and obesity-related complications.