Nature Medicine, Published online: 10 January 2025; doi:10.1038/s41591-024-03463-z
In a crossover trial evaluating semaglutide versus placebo as an add-on to automated insulin delivery therapy in adults with type 1 diabetes, the use of semaglutide was associated with an increased percentage of time spent within the target glucose range, along with reduced insulin requirements.- January 10, 2025
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Nature Medicine, Published online: 10 January 2025; doi:10.1038/s41591-024-03406-8
Results from the phase 2 MATCH01 clinical trial of autologous monocyte-derived macrophage therapy for liver cirrhosis revealed no liver-related severe adverse events or deaths in the treatment group.- January 10, 2025
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Continue reading "11 benefits of adding delicious almonds to your winter diet"
- January 9, 2025
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Continue reading "Ghee benefits: 7 reasons this dairy delight is a must-have"
- January 9, 2025
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Nature Medicine, Published online: 09 January 2025; doi:10.1038/s41591-024-03431-7
An individual-based mathematical model evaluating the public health benefits of RSVpreF vaccination showed that vaccinating older adults and pregnant women can substantially reduce respiratory syncytial virus (RSV)-related hospitalizations and deaths, averting substantial inpatient costs, with the impact varying across countries and influenced by both uptake rates and the local epidemiological characteristics of RSV seasons.- January 9, 2025
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Nature Medicine, Published online: 09 January 2025; doi:10.1038/s41591-024-03442-4
Premarital genomic screening in Arab populations of the Middle East- January 9, 2025
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Nature Medicine, Published online: 08 January 2025; doi:10.1038/s41591-024-03429-1
In the second case in which a genetically modified pig heart was transplanted into a living person, the xenografted heart functioned well initially, but antibody-mediated rejection occurred thereafter, pointing to the need for improved strategies to avoid this complication.- January 8, 2025
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Nature Medicine, Published online: 08 January 2025; doi:10.1038/s41591-024-03458-w
This analysis of the registry database DESCAR-T of more than 3,000 pediatric and adult patients with hematological malignancies who received CAR T cell therapy in France between 2018 and 2024 shows that only one person developed a secondary T cell malignancy following CAR T cell therapy.- January 8, 2025
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Nature Medicine, Published online: 08 January 2025; doi:10.1038/d41591-025-00001-3
Satellite data assessing residential greenness across Italy indicate that thousands of deaths could be prevented by greening residential areas.- January 8, 2025
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Nature Medicine, Published online: 08 January 2025; doi:10.1038/s41591-024-03455-z
KRAS mutations are ubiquitous in pancreatic adenocarcinomas (PDACs) and are associated with poor outcomes. We leveraged a cohort of 2,336 PDAC tumors to characterize genomic subtypes and their prognostic correlates across clinical stages. A key finding is that shallow copy gains in KRAS mutant alleles are common and indicate unfavorable prognosis.- January 8, 2025
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