health

Nature Medicine, Published online: 28 July 2025; doi:10.1038/s41591-025-03828-y

In a large cross-national study, education was linked to better memory and larger brain volumes but not to slower cognitive or brain decline with age, suggesting that the association reflects early-life factors rather than neuroprotective effects in aging.

Nature Medicine, Published online: 28 July 2025; doi:10.1038/s41591-025-03857-7

Resurging violence in Colombia is silently embedding a syndemic mental and brain health crisis driven by trauma, mass displacement, and ecological collapse.

Nature Medicine, Published online: 28 July 2025; doi:10.1038/s41591-025-03829-x

The 2025 Pandemic Agreement is a grand global social bargain that replaces charity with equity.

Nature Medicine, Published online: 25 July 2025; doi:10.1038/s41591-025-03814-4

By analyzing the levels of thousands of proteins in blood samples from approximately 50,000 people, researchers estimate how biologically ‘old’ individual organs appear. When estimated organ age is older than a person’s actual age, risk of disease and earlier death increase, whereas a youthful brain and immune system signal a longer, healthier life.

Nature Medicine, Published online: 25 July 2025; doi:10.1038/s41591-025-03858-6

Now is the time to recognize and respond to addiction to ultra-processed foods

Nature Medicine, Published online: 25 July 2025; doi:10.1038/s41591-025-03905-2

In an updated report on 70 laboratory-confirmed highly pathogenic avian influenza A H5N1 cases in the United States between March 2024 and May 2025, the absence of human to human transmission to date was confirmed, with no known mutations of resistance to neuroaminidase inhibitors.

Nature Medicine, Published online: 25 July 2025; doi:10.1038/s41591-025-03903-4

Editorial Expression of Concern: Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation

Nature Medicine, Published online: 24 July 2025; doi:10.1038/d41591-025-00046-4

A prospective implementation study shows how a low-cost, swallowable capsule sponge could be used for regular monitoring and risk stratification in people with Barrett’s esophagus, offering a minimally invasive alternative to endoscopy.

Nature Medicine, Published online: 24 July 2025; doi:10.1038/s41591-025-03845-x

Positive results from a first-in-human clinical trial validate the ANGPTL3–ANGPTL8 complex as a new therapeutic target for reducing triglycerides and, potentially, cardiovascular disease risk.

Nature Medicine, Published online: 24 July 2025; doi:10.1038/s41591-025-03804-6

Laurence Zitvogel reflects on the essential contribution of the immune system to the efficacy of anticancer chemotherapy.