Nature Medicine, Published online: 26 June 2025; doi:10.1038/s41591-025-03810-8
We developed CANSCAN, a blood test that analyzes multidimensional features of cell-free DNA (cfDNA) using whole-genome sequencing (WGS) and artificial intelligence (AI) models. This multi-cancer early detection (MCED) test demonstrates high sensitivity for early-stage cancers and accurate tissue-of-origin prediction in large prospective validation and asymptomatic screening cohorts.- June 26, 2025
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Nature Medicine, Published online: 26 June 2025; doi:10.1038/s41591-025-03797-2
Jeffrey Friedman recalls the heady excitement when his group discovered leptin, a hormone that regulates appetite.- June 26, 2025
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Nature Medicine, Published online: 26 June 2025; doi:10.1038/s41591-025-03825-1
To capture the changing rather than one-off risk of type 1 diabetes (T1D), we developed an artificial intelligence-driven microRNA-based multi-context (5,983 samples from 7 countries) dynamic risk score (DRS). We validated that this DRS enabled T1D discrimination, misdiagnosis correction and therapeutic response prediction, establishing a personalized, adaptive framework for T1D risk monitoring and intervention.- June 26, 2025
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Nature Medicine, Published online: 26 June 2025; doi:10.1038/s41591-025-03852-y
Author Correction: Allogeneic NK cells with a bispecific innate cell engager in refractory relapsed lymphoma: a phase 1 trial- June 26, 2025
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Nature Medicine, Published online: 25 June 2025; doi:10.1038/s41591-025-03776-7
In a reverse-translational study followed by a clinical trial, the targeting of antigen-presenting mast cells was identified as a therapeutic approach to overcome anti-PD-1 resistance in patients with metastatic triple-negative breast cancer who experienced clinical benefit when treated with the mast cell stabilizer cromolyn.- June 25, 2025
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Nature Medicine, Published online: 25 June 2025; doi:10.1038/s41591-025-03771-y
Using mathematical models calibrated to clinical trial results on vaccine efficacy, this study projects the potential impact of the vaccine at population level, showing the conditions for it to be effective in reducing cases and hospitalizations and helping to design vaccination campaigns.- June 25, 2025
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Nature Medicine, Published online: 25 June 2025; doi:10.1038/s41591-025-03772-x
As neural implants become more integrated with human cognition and identity, the risks posed by their sudden discontinuation are unique and demand urgent attention.- June 25, 2025
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Nature Medicine, Published online: 25 June 2025; doi:10.1038/s41591-025-03740-5
A new study identifies a novel subset of mast cells that cross-present tumor antigens in patients triple-negative breast cancer — and a pilot clinical trial shows how these can be exploited in immunotherapy strategies.- June 25, 2025
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Nexira brings targeted solutions for formulators eager to capitalize on this vibrant space. From precision prebiotics to botanical extracts and natural texturizers, Nexira’s booth will be a destination for inspiration and innovation across multiple market segments.
- June 24, 2025
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EXBERRY Organics Brilliant Pink is a liquid-based concentrate made from purple sweet potatoes grown in compliance with both EU and US organic standards. It is created using physical processing methods and supports simple label declarations, such as “concentrate (sweet potato*)” (*from certified organic agriculture) in the EU and “organic vegetable juice for color” in the US.
- June 24, 2025
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