wellness

Nature Medicine, Published online: 20 February 2026; doi:10.1038/s41591-026-04225-9

The diagnostic phase of a population-based colorectal cancer screening trial involving over 270,000 Swedish adults found that colonoscopy or fecal immunochemical testing both increased the proportion of diagnoses of early-stage cancers relative to usual care.

Nature Medicine, Published online: 20 February 2026; doi:10.1038/s41591-026-04230-y

How to accelerate cures for genetic diseases using an artificial intelligence-enabled discovery engine to identify druggable nodes and develop clinical targets.

Nature Medicine, Published online: 20 February 2026; doi:10.1038/d41591-026-00010-w

Researchers show that in mice, tumor-secreted cystatin-C crosses the blood–brain barrier and stimulates microglia to degrade amyloid plaques, which opens interesting avenues for translational clinical studies.

Nature Medicine, Published online: 20 February 2026; doi:10.1038/d41591-026-00011-9

When used as intended, an AI stethoscope enhanced the detection of cardiovascular disease — but low uptake and workflow challenges hampered effectiveness in a large pragmatic trial.

Nature Medicine, Published online: 19 February 2026; doi:10.1038/s41591-026-04238-4

In a case series of five patients with treatment-refractory antisynthetase syndrome and five patients with treatment-refractory systemic sclerosis, bispecific T cell engagers blinatumomab and teclistamab improved disease activity and were well tolerated.

Nature Medicine, Published online: 19 February 2026; doi:10.1038/s41591-026-04206-y

Plasma p-tau217 tests used to develop clocks that predict when cognitively unimpaired individuals would develop symptoms of Alzheimerʼs disease.

The 2026 ASC ratings will feature more high performing facilities.

Nature Medicine, Published online: 18 February 2026; doi:10.1038/s41591-026-04235-7

This multidisciplinary response to investigate the large outbreak of unknown febrile illness in the Panzi Health Zone in the Democratic Republic of the Congo in late 2024 suggests that the outbreak was largely associated with malarial cases and concurrent viral respiratory infections.

Nature Medicine, Published online: 18 February 2026; doi:10.1038/s41591-026-04201-3

Stem-cell-derived islet cells could transform type 1 diabetes by removing the need for injected or infused insulin and improving quality of life. But evaluation of these therapies must center on the voices of people living with type 1 diabetes and examine meaningful outcomes.

February was officially designated Black History Month in the United States in 1976 by President Gerald Ford. But long before that, in 1926, the Association for the Study of Negro Life and History declared the second week of the month “Negro History Week” to honor the achievements of Black Americans in U.S. history. The reason the organization chose that week? It includes the birthdays of both abolitionist Frederick Douglass and former U.S. president Abraham Lincoln.