wellness

Nature Medicine, Published online: 07 March 2025; doi:10.1038/s41591-025-03575-0

Exploratory post hoc analysis of molecular residual disease (MRD) from the ADAURA trial of adjuvant osimertinib in patients with resected EGFR-mutated stage IB–IIIA non-small cell lung cancer shows that MRD detection predicts disease recurrence with long term adjuvant osimertinib treatment.
  • March 7, 2025
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Nature Medicine, Published online: 07 March 2025; doi:10.1038/s41591-025-03556-3

A randomized clinical trial showing the superiority of behavioral treatment plus phentermine to behavioral treatment plus placebo for weight loss in those that previously had not responded to behavioral treatment.
  • March 7, 2025
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Nature Medicine, Published online: 07 March 2025; doi:10.1038/s41591-025-03558-1

This Perspective explains how past migrations and environmental exposures have influenced genomic diversity, and how understanding and contextualizing this diversity is crucial to advancing precision medicine and equitable healthcare.
  • March 7, 2025
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Nature Medicine, Published online: 07 March 2025; doi:10.1038/s41591-025-03579-w

An updated analysis of the DYNAMIC biomarker-driven trial, including mature survival data at 5 years, supports a ctDNA-guided approach to adjuvant chemotherapy for stage II colon cancer.
  • March 7, 2025
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You may be having beetroot juice as a pre-workout drink or pairing it with your breakfast to support heart health. Yes, there are multiple benefits of drinking the beverage, which is made by extracting the liquid from the root of a raw or cooked beetroot plant. It contains betalains and nitrates along with vitamin C …
  • March 6, 2025
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Natural products industry sales were expected to hit nearly $320B in 2024 with growth across virtually every department. In advance of Natural Products Expo West, Prepared Foods covers everything from innovation to ingredients with Scott Dicker, market insights director at SPINS LLC, Chicago.

  • March 6, 2025
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Nature Medicine, Published online: 06 March 2025; doi:10.1038/s41591-025-03574-1

Spatial transcriptomics reveals distinct microglial mechanisms driving amyloid-β clearance in both passively and actively immunized patients with Alzheimer’s disease.
  • March 6, 2025
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Nature Medicine, Published online: 05 March 2025; doi:10.1038/s41591-025-03560-7

Using longitudinal survey and neuroimaging data from more than 11,000 adolescents in the United States, a machine learning model shows promising performance in identifying individuals at greater risk of transitioning to psychopathology, pinpointing sleep disturbances as the most predictive risk factor.
  • March 5, 2025
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Nature Medicine, Published online: 05 March 2025; doi:10.1038/s41591-025-03566-1

Secondary and exploratory analyses of the phase 3 NRG GY018 trial show that, in patients with advanced or recurrent endometrial cancer, first-line treatment with pembrolizumab together with paclitaxel and carboplatin leads to prolonged progression-free survival, according to blinded independent central review.
  • March 5, 2025
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Nature Medicine, Published online: 05 March 2025; doi:10.1038/s41591-025-03546-5

Leveraging implementation science in clinical trials of vaccines in the global south
  • March 5, 2025
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