Tislelizumab plus zanubrutinib for Richter transformation: the phase 2 RT1 trial
Nature Medicine, Published online: 09 December 2023; doi:10.1038/s41591-023-02722-9
In a large single-arm phase 2 trial, the anti-PD-1 inhibitor tislelizumab combined with the next-generation BTK inhibitor zanubrutinib had an overall response rate of 58.3% and was well tolerated in patients with Richter’s transformation.
Tislelizumab plus zanubrutinib for Richter transformation: the phase 2 RT1 trial
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