Unlocking the broad health benefits and risks of GLP-1 receptor agonist drugs

Unlocking the broad health benefits and risks of GLP-1 receptor agonist drugs

Nature Medicine, Published online: 23 January 2025; doi:10.1038/s41591-024-03476-8

This study systematically analyzed 175 health outcomes in 2 million people using glucagon-like peptide-1 receptor agonists (GLP-1RAs) or other antihyperglycemics. GLP-1RAs reduce risks of neurocognitive, substance use, cardiovascular and respiratory disorders, but increase risks of gastrointestinal issues, hypotension and pancreatitis. The study provides important insights for clinical practice and future research.

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Unlocking the broad health benefits and risks of GLP-1 receptor agonist drugs

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