Using genetics as a tool to understand female reproductive health better
Nature Medicine, Published online: 02 April 2025; doi:10.1038/s41591-025-03663-1
Genome-wide association analyses of 42 female reproductive disorders identify 195 associations between genetic variants and reproductive health traits, including previously unidentified risk factors for ovarian cysts and uterine fibroids. We characterize the genetic architecture of studied traits and highlight the potential of a polygenic risk score to enhance risk prediction for intrahepatic cholestasis of pregnancy.
Using genetics as a tool to understand female reproductive health better
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