Using genetics to predict toxicity of cancer immunotherapy

Using genetics to predict toxicity of cancer immunotherapy

Nature Medicine, Published online: 16 December 2022; doi:10.1038/s41591-022-02096-4

A variant of the IL7 gene predicts the toxicity of checkpoint inhibitors in patients with cancer, via a mechanism shared with autoimmune diseases — which could inform biomarker and treatment strategies in both of these contexts.

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Using genetics to predict toxicity of cancer immunotherapy

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