Ustekinumab for type 1 diabetes in adolescents: a multicenter, double-blind, randomized phase 2 trial

Ustekinumab for type 1 diabetes in adolescents: a multicenter, double-blind, randomized phase 2 trial

Nature Medicine, Published online: 30 July 2024; doi:10.1038/s41591-024-03115-2

A phase 2 randomized controlled trial of ustekinumab in 72 adolescents with recent-onset type 1 diabetes showed that treatment was well tolerated and β-cell function was 49% higher in the intervention group compared to the placebo arm after 12 months.

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Ustekinumab for type 1 diabetes in adolescents: a multicenter, double-blind, randomized phase 2 trial

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