IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma

IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma

Nature Medicine, Published online: 16 December 2022; doi:10.1038/s41591-022-02095-5

Genetic analyses in a cohort of patients with melanoma receiving immunotherapy reveal that variants in IL7 are associated with immune-related adverse events and highlight the role of B cells in mediating toxicity.

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IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma

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